Sacubitril/Valsartan

Brand names: Entresto

Sacubitril/valsartan is a combination medication used to treat chronic heart failure with reduced ejection fraction. It combines a neprilysin inhibitor (sacubitril) with an angiotensin receptor blocke

ARNI (Angiotensin Receptor-Neprilysin Inhibitor)
Prescription Required
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Table of Contents

At a Glance

What is it?
Sacubitril/valsartan is a combination medication used to treat chronic heart failure with reduced ejection fraction. It combines a neprilysin inhibito
Drug Class
ARNI (Angiotensin Receptor-Neprilysin Inhibitor)

Overview

Sacubitril/valsartan is a combination medication used to treat chronic heart failure with reduced ejection fraction. It combines a neprilysin inhibitor (sacubitril) with an angiotensin receptor blocker (valsartan) to reduce the strain on the heart and has been shown to reduce hospitalization and death from heart failure.

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Sources & References

  1. FDA Drug Label Information — fda.gov
  2. National Library of Medicine (DailyMed) — dailymed.nlm.nih.gov
  3. MedlinePlus Drug Information — medlineplus.gov
  4. American Pharmacists Association — pharmacist.com
  5. National Institutes of Health (NIH) — nih.gov
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